HEMATOLOGICAL CHANGES AND NUTRITIONAL CHANGES IN RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS PATIENT AS COMPARED TO CONTROL

Background: Rheumatoid Arthritis is a chronic multisystem disease of unknown etiology. The characteristic feature of Rheumatoid arthritis is persistent inflammatory synovitis, usually involving peripheral joints in a symmetric distribution. Hematologic disorders including anemia, white blood cells abnormalities, platelet abnormalities, coagulopathy and hematological malignancies can be manifested in many autoimmune rheumatic diseases Objective: The objective of this study to calculate the energy intake and check the hematological changes in study group and compared with control. Material and Methods: The study was undertaken in the Department of Biochemistry, S.R.N. Hospital and Medical College Allahabad. In this study 300 samples collected of the age 20-70 year. In which 100 normal individuals they are free from any disease and 100 OA and RA patient collected. Conclusion: On the basis of data we have conclude that arthritis patients have lower level of hemoglobin, higher levels of hemolysis and ESR as compared to control. Lower level of Hb, Iron and increased levels of TIBC is a marker of IDA and ACD which plays a significant role in the etiopathogenesis in Anemia in Rheumatoid arthritis and Osteoarthritis.