Effect of Clopidogrel on the Levels of Adropin and Adiponectin in Serum of Female Albino Rats

Clopidogrel is an antiplatelet drug. It helps hold blood flowing smoothly in body, used to save you coronary heart attacks and strokes in individuals with heart disease, recent stroke, or blood movement disease. It is also used to keep blood vessels open and prevent blood clots after sure processes. Adropin is a unique hormone encode via the electricity homeostasis-associated. Adropin is produce within the liver and brain, and additionally in peripheral tissues inclusive of inside the heart and gastrointestinal tract. Furthermore, adropin is present inside the circulatory machine. Adiponectin is a hormone and an adipokine protein that influences several metabolic tactics and is specially recognised for its insulin-sensitizing and anti-inflammatory results. Adipose tissue is specially responsible for generating adiponectin, though other tissues in frame crop it as properly. The relationship between the Glopidogrel and adropin, adiponectin is still not clear. The aim of the study is to determine adropin and adiponectin attentiveness in serum male rats that treated with Clopidogrel, and to examine the relationship amid serum adropin and adiponectin. Materials and strategies: fifteen healthy adult female albino rats have been used for this examine. The rats had been randomly and equally alienated into three businesses. Group-A; control group, group-B; given 15mg/kg Glopidogrel, and groupC; given 20mg/kg Glopidogrel. Results: this study revealed rats which treated with Glopidogrel showed significantly increased in serum adropin and adeponectin levels comparison with control group.