BREAST CARCINOMA WITH LOBULAR COMPONENT DISCOVERED BY THYROIDMETASTASIS: A CASE REPORT
Journal: International Journal of Advanced Research (Vol.11, No. 12)Publication Date: 2023-12-15
Authors : Amirath A. Sanni Habiba A. Mariam Ahlam Bassir Bouchra Fakhir Karam Harou Lahcen Boukhanni Abderrahim Aboulfalah Hamid Asmouki; Abderraouf Soummani;
Page : 114-119
Keywords : Lobular Breast Carcinomas Thyroid Metastasis Thyroidectomy;
Abstract
Objective: Breast cancer is the most common cause of cancer-related deaths and is frequently diagnosed in women worldwide. The purpose of this study is to report a case of breast carcinoma with lobular component discovered through thyroid metastasis at the Mohammed VI University Hospital in Marrakech. Case presentation: The patient, a 59 year old multiparous postmenopausal woman with a history of diabetes and hypertension, was referred from the ENT department for a thyroid localization of a carcinomatous process of mammary origin, incidentally discovered during total thyroidectomy + lymph node dissection. A cervical mass had been evolving for approximately 2 years. Results: Physical examination revealed a cervical scar from thyroidectomy, along with an ulcerated lesion of the left breast measuring 2 x 2 cm in the sub-mammary groove, without palpable nodules or lymphadenopathy. Cervical CT scan showed a multinodular and heterogeneous cervical goiter, leading to the recommendation of total thyroidectomy + lymph node dissection. Histopathological examination with immunohistochemistry confirmed a thyroid localization of a mammary-origin carcinomatous process, specifically lobular type. Bilateral mammography revealed two lesions in the left upper outer quadrant and one near the left sub-mammary groove, associated with a left axillary lymph node classified as ACR 5. Biopsy of the sub-mammary lesion identified an infiltrating non-specific type of breast carcinoma with lobular differentiation, classified as luminal B. Following a multidisciplinary consultation, neoadjuvant chemotherapy AC60-Docetaxel + left patey post-chemotherapy was decided upon. Conclusion: Breast cancer metastases to the thyroid, as observed in this study, are rare. Only a few studies (39 cases) have reported this type of breast cancer metastasizing to the thyroid, highlighting the uniqueness of this studyin a southern country. Subject Areas: Gynecology & Obstetrics.
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