Minimal Deviation Adenocarcinoma of The Cervix: Still A Gynecologist Oncologist’s Nightmare |Biomedgrid

Minimal deviation adenocarcinoma (MDA) is a rare neoplasm characterized by difficult diagnosis, no standard treatment and poor prognosis. This neoplasm accounts for 1 to 3% of all cervical adenocarcinoma, and the mean age of the patients at the time of diagnosis is 45 years old. It has a characteristic endophytic growth pattern; conventional methods for cervical cancer screening frequently fail. Here we report the case of a 44-year-old woman that underwent only medical therapy, pointing out the problems we met during the diagnosis path and the treatment planning. She came to our attention for vaginal bleeding and with pap smear that showed no cytological alterations. MRI showed polycystic and solid component enhancement, and we performed conoid biopsy twice, because the first one was not decisive. She died twenty-one months after the diagnosis.