The Gut Microbiome, Aging and Longevity An Overview

The gut microbiome is a contributory factor in ageing related health loss and in several non communicable diseases in all age groups. Some age linked and disease linked compositional and functional changes overlap, while others are distinct. The gut microbiota undergoes extensive changes across the lifespan, and age related processes may influence the gut microbiota and its related metabolic alterations. The aim of this systematic review was to summarize the current literature on aging associated alterations in diversity, composition, and functional features of the gut microbiota. Longevity is one of the most complex phenotypes, and its genetic basis remains unclear. This study aimed to explore the genetic correlation and potential causal association between gut microbiota and longevity. Human longevity has a strong familial and genetic component. Dynamic characteristics of the gut microbiome during aging associated with longevity, neural, and immune function remained unknown. Here, we aim to reveal the synergistic changes in gut microbiome associated with decline in neural and immune system with aging and further obtain insights into the establishment of microbiome homeostasis that can benefit human longevity. In this paper we will discuss The Gut Microbiome, Aging and Longevity an Overview. Dr. G. Renuka | K. Vaishnavi | L. Vijayalaxmi | P. Srihitha | R. Himabindu "The Gut Microbiome, Aging and Longevity- An Overview" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-6 , December 2023, URL: https://www.ijtsrd.com/papers/ijtsrd61302.pdf Paper Url: https://www.ijtsrd.com/biological-science/microbiology/61302/the-gut-microbiome-aging-and-longevity-an-overview/dr-g-renuka