Ocular Presentation of Behcet’s Syndrome Associated with Covid-19 Vaccination |Biomedgrid

Purpose: To shed some light on the long debate as to whether autoimmune diseases might also be triggered by vaccines, through the immune cross-reactivity mechanism. Observations: We report a case of bilateral pan uveitis and vasculitis, being a first presentation of Behcet syndrome in a young healthy patient who received COVID-19 vaccine. The vaccine might have triggered de novo ocular inflammatory process or ocular exacerbation of an impending Behcet disease, through the immune cross-reactivity mechanism. The patient was treated with oral prednisone and azathioprine with good response. Conclusions and Importance: In our case it might be due to de novo ocular inflammatory process or due to ocular exacerbation of an impending Behcet disease, both might have been triggered by the COVID-19 vaccine the patient received It is important for clinicians to be aware of the association we encountered, and for future post-marketing studies of COVID-19 vaccine to address it.