Can We Use N-Acetylcysteine as An Antioxidant In SARS-Cov-2 Treatment? A Pathophysiology Review |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.16, No. 1)Publication Date: 2022-03-30
Authors : Rawan Eskandarani; Baian Abdulbaqi;
Page : 16-21
Keywords : Proinflammatory cytokines; Nuclear factorkappa; Macrophages; Bronchial; Angiotensin;
Abstract
The Coronavirus disease of 2019 (COVID-19) was first identified in Wuhan (Hubei, China) in December 2019 [1] the virus responsible for this disease was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In March of 2020, it was declared by the World Health Organization as a pandemic [2]. Within the coronavirus (Coronaviridae) family, the Alphacoronavirus and Beta coronavirus subfamily are known to be transmissible to humans [3]. Clinical symptoms vary widely, but the Beta coronavirus strains MERS-CoV (Middle East respiratory syndrome coronavirus), SARS coronavirus (severe acute respiratory syndrome coronavirus) now named SARS-CoV-1, and SARS-CoV-2 (the causing agent for COVID-19) seems to be of the most pathogenic strains of the group [4].
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