Mass Spectrometry Analysis of Novel Stem Cell-Derived Peptides |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.16, No. 2)Publication Date: 2022-04-26
Authors : Alicia Wells; Adam Good; Kimia Damyar; Michael Alexander; Ben Katz; Mike K.S.Chan; Michelle B.F.Wong; Desiree Cox; Dmytro Klokol; Jonathan RT Lakey;
Page : 232-239
Keywords : Peptides; Nano Organo Peptides (NOP); Mito Organelles (MO) Peptides; Mass Spectrometry; Mitochondriaspecific functions;
Abstract
Short peptides have been demonstrated to play an important role in modulating transcription, the transmission of biological information, and in restoring the genetic alterations that occur with aging. This paper aims to describe a method of identifying a population of peptides derived from a peptide cocktail formulation. Samples of Nano Organo Peptides (NOP) and Mito Organelles (MO) Peptides derived from both the Central Nervous System (CNS) and the Lungs (LBS) of Specific Pathogen Free (SPF) mammalian rabbits sourced from Charles River Labs were analyzed by mass spectrometry and chromatograms were generated for further examination. The experimentally derived peaks were searched against a database of known proteins to identify the peptides present in each sample. The following report outlines the experimental methods and the results from performing mass spectrometry on various peptides from the company European Wellness (EW).
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