Postnatal Organellogenesis in Histaminergic Neurons of the Rat Brain |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.16, No. 2)Publication Date: 2022-04-26
Authors : Sergey M Zimatkin; Anastasia V Zaerko; Ekaterina M Phedina; Nikita A Valko;
Page : 256-264
Keywords : Hypothalamus; Histaminergic Neurons; Cell Membrane; Nuclear Envelope; Organellogenesis;
Abstract
The organellogenesis of histaminergic neurons in the nucleus E2 of the rat hypothalamus on the 5th, 20th, and 45th days of postnatal development was described using the electron microscopic method of investigation. It has been established that during the described period of development in histaminergic neurons the number of mitochondria and the relative area occupied by them in the cytoplasm increase, the mitochondria acquire an elongated shape, and the length of the cristae increases in them. The number of bound ribosomes on the rough endoplasmic reticulum cisternae increases, while the number of free ribosomes does not change, the Golgi complex develops progressively, and the number of lysosomes and, accordingly, the relative area occupied by them in the cytoplasm also increase.
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