A Comprehensive Review of Currently Researched Medicinal Herbs with Anticoagulant Potential

Various herbal preparations have been used since ancient times to solve clotting problems. It is considered more affordable to target the side effects of synthetic coagulants, relying mainly on herbal medicines. According to the World Health Organization (WHO), 80 percent of the world's population depends on primary health care. Important pharmacological effects have been observed when using herbal medicines. This article provides an updated and comprehensive review of plants and phytoconstituents known to have antiplatelet and anticoagulant effects. The review presents various bioactive compounds and secondary metabolites, such as alkaloids, tannins, saponins, glycosides, flavonoids, coumarins, sesquiterpenes and polyphenols, which are said to be responsible for antiplatelet and antithrombotic effects. The purpose of this study is to document the effects of natural anticoagulants. Analysis of selected literature showed that many plants contain bioactive compounds with antiplatelet and anticoagulant effects. These herbal ingredients act against factors that play an important role in thrombosis by disrupting primary and secondary hemostasis. The potential of herbal ingredients to fight various diseases suggests the need for further research. Referenced articles were retrieved from Google Scholar, PubMed, ScienceDirect and Elsevier, focusing on articles published in English-language journals. Together, this study highlights the importance of new phytoconstituents to minimize the adverse effects of current anticoagulants