CLINICAL CHARACTERISTICS, QUALITY OF LIFE AND COMORBID PATHOLOGY OF PATIENTS WITH PSORIASIS
Journal: Journal of the Grodno State Medical University (Vol.22, No. 1)Publication Date: 2024-03-12
Authors : A. V. Brynina;
Page : 56-60
Keywords : psoriasis; comorbidity; combined pathology; quality of life;
Abstract
Background. Psoriasis is a chronic relapsing dermatosis, with a dominant genetic basis, characterized by hyperproliferation and impaired differentiation of epidermal cells, an inflammatory reaction in the dermis, and numerous biochemical, vascular and immunological abnormalities. The purpose is to study the frequency of individual skin symptoms, to assess the quality of life and concomitant pathologies in patients with psoriasis who received treatment at the Grodno Regional Clinical Dermatovenerological Dispensary. Material and methods. The study involved 57 patients, of which 60% were men and 40% were women. The median age was 47 years. The clinical characteristics and concomitant diseases in patients with psoriasis, the Psoriasis Area and Severity Index (PASI index) and the Dermatological Quality of Life Index (DQLI) were assessed. Results. 57 patients took part in the survey, of which 34 were men (60%) and 23 women (40%). The median age was 47 years. When analyzing the frequency of individual skin symptoms, the most frequently noted lesions were the scalp and seborrheic areas, 73.7% and 59.6%, respectively. The median value of the PASI index was 20.0, with a minimum value of 9 and a maximum of 48. Among the examined patients, the median of the DLQI index was 10 points, and more than 50% indicated a “moderate” decrease quality of life. Among the 57 patients surveyed, 27 (47%) had concomitant diseases. When considering the nature of comorbid conditions, diseases of the cardiovascular system and hypercholesterolemia with dyslipidemia were most often observed in patients with psoriasis, 26.3% and 21.1% according to general survey indicators. Conclusions. The problems of combined pathology in patients with psoriasis are relevant and require further indepth study and the search for scientifically based solutions that will improve the quality of medical care for patients with both isolated psoriasis and its combined course.
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Last modified: 2024-03-12 22:02:53