Heme Enzymes: Nature’s Versatile Catalysts |Biomedgrid

Heme enzymes are ubiquitous in nature. Although these enzymes contain the same Fe-protoporphyrin IX cofactor in their active site, they exhibit different structural and functional activities. This brief review focuses on the reasons for this diversity and mentions some attempts to mimic the structural and functional activity of these heme enzymes. It also briefly discusses efforts to expand their catalytic repertoire to enable new chemical transformations.