Circadian Rhythm-Related Molecular Mechanisms and Chemotherapy |Biomedgrid

Cancer cells manipulate the biological clock that regulates the functioning of the body to regulate their own rhythms. It is known that the biological clocks of individuals with cancer activate tumor cells and feed them. The genes and gene products of the circadian clock that make up our biological rhythm have a critical role in the physiological pathways that are important for cell metabolism. The cell cycle and the circadian rhythm are in constant interaction, and circadian clock genes and gene products are involved in the control of the cell cycle. Although circadian control and the cell cycle are composed of different molecular mechanisms, these two cycles are interrelated in mammals. Because circadian clock gene mutations can alter the expression of important cell cycle regulators. Therefore, it is a fact that the circadian clock is associated with the regulation of cell division. In short, the cell cycle and the circadian clock are generally the regulatory systems of all organisms.