ADMET ANALYSIS OF TRIAZOLE DERIVATIVE: A THEORETICAL INVESTIGATION TOWARDS ITS EVALUATION AS A DRUG CANDIDATE
Journal: International Journal of Advanced Research (Vol.12, No. 03)Publication Date: 2024-03-20
Authors : Shreyas S. Siddaramanna S.C. Keerthana R.K. Roopini B.M. Rakesh B.R.; Smitha Patil;
Page : 439-443
Keywords : Lipinskis Rule of Five Toxicity Triazole Derivative;
Abstract
The present work explores the potency of the 3-Ethoxy-5-phenyl-1H-1,2,4-triazole compound using in-silico experimental techniques. The compound was subjected to ADMET analysis to understand how well the compound can be used as drug. Further the ADMET analysis revealed that the compound showed excellent pharmacokinetic properties with all the values were found to be well within the limits. Further various properties of the compound were evaluated and the boiled egg model analysis revealed that the compound good gastrointestinal absorption property. The toxicity value of the compound were also evaluated.
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Last modified: 2024-04-04 13:11:09