ROLE OF PRP IN DIABETIC FOOT ULCER

Introduction: Diabetic Foot Ulcers (Dfus) are among the most common complications of diabetes mellitus with a lifetime incidence of up to 15% among the diabetic population. Current standard management consists of surgical debridement followed by frequent dressing changes with tight infection and glycemic control. Despite this comprehensive approach, complication and amputation rates remain high. A newer treatment modality PRP gel dressing is being investigated. Method:This study is a prospective comparative study done in Dept of General Surgery for period of 9 months with 30 diabetic patients with chronic non healing foot ulcer. PRP dressings were done biweekly for 8 weeks. Result: 80% patients in present study were more than 40yrs.Hypertension was present in 80% of patients in both control and PRP group and hyperlipidemia was present in 66% of control group and 73% in PRP group. After regular biweekly dressing with PRP gel, by the end of eight weeks PRP dressing patients showed better wound healing with p value < 0.05 In PRP dressing group rate of ulcer healing was found to be maximum in 4 weeks after which this rate declined. Conclusion:The present study supports the conclusion that autologous PRP gel does effectively accelerate wound healing in clean diabetic foot ulcers when compared with the conventional saline gauze antiseptic dressing.