Clinicopathological Assessment of Colorectal Polyps in a Sample of Iraqi Patients
Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.7, No. 2)Publication Date: 2024-02-15
Authors : Zainab Mohammed Ahmed; Alaa G. Hussein;
Page : 29-35
Keywords : ;
Abstract
Background: Globally, colorectal carcinoma is considered second most common cancer in women and third most common cancer in men. Aim: to evaluate and determine histopathological types of different colorectal polyps in a sample of Iraqi patients, and to correlate this with clinicopathological parameters. Methods and materials: A retrospective cross-sectional study included 105 cases, which were retrospectively evaluated to determine histopathological type of different colorectal polyps. Results: mean age of cases was 53.8 ± 16.8 years old. Male to female ratio of 2:1. majority of cases have a polyp in single location within large bowel. There were 43.8% of cases had sigmoid involvement. Regarding type of polyps, sessile polyp was presented in 60.9% of cases and pedunculated polyp was presented in 36.1% of cases. histopathological type showed that, 57.1% of cases had neoplastic polyps, 38.1% had non-neoplastic polyps, and 4.8% cases had both (neoplastic and non-neoplastic polyps). majority of cases with neoplastic polyps were adenomas [57 cases (95%) without FAP and 2 (3.3%) cases with FAP], while adenocarcinoma was reported in a single case only. Thirty Six cases (63.1%) of adenoma presented with tubular adenoma with low grade atypia. Conclusion: Predominance of male gender which was comparable to worldwide studies. neoplastic polyps were most common type of polyp that showed an association with age, number, size, and gross morphology of polyps. majority of cases with neoplastic polyps were adenomas (tubular adenoma) with low grade of atypia. Hyperplastic polyps were most common type of non-neoplastic polyps
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