The Efficacies and Safety of Probiotics of Lactobacillus Rhamnosus GR-1 and Lactobacillus Reuteri RC-14 in Female Vaginal Infections Without Anti-Biotics: A Clinical Trial |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.16, No. 5)Publication Date: 2022-06-28
Authors : Dan Cheng; Long Cheng; Shadow Zhang;
Page : 562-566
Keywords : Antibiotics; Probiotics; Leucorrhea; Menstruation; Environment;
Abstract
It is urgent and imperative to find an alternative treatment for vaginal infections due to large population of female individuals susceptible of vaginal infections and low efficacies of traditional antibacterial medication and cleansing gels. There have already been clinical studies for applying probiotics in treating vaginal infections. Our trial is the first large scale investigation of 348 female individuals with vaginitis on treatment of probiotics including Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in female vaginal infections without antibiotics. After orally supplementation of two strains for 28 days, over 90% female individuals were satisfied with the treatment regarding the improvement in ten symptoms. The trial provided a valuable target for treating vaginitis especially for vulnerable female subjects with the application of GR-1 and RC-14 alone while no safety issues occurred.
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