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UNUSUAL ASSOCIATION OF MENINGIOMA AND PITUITARY HYPOPLASIA IN A PATIENT WITH OSTEOGENESIS IMPERFECTA

Journal: International Journal of Advanced Research (Vol.12, No. 04)

Publication Date:

Authors : ; ;

Page : 721-724

Keywords : Osteogenesis Imperfecta Connective Tissue Meningioma Pituitary Hypoplasia;

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Abstract

Osteogenesis imperfecta (O.I.) is a rare inherited disorder that alters the physiological structure of connective tissue. In some cases, several neurological features have been described. We report.the case.of.a.10years old boy with a knownfamilyhistory of type I OI who suffered from repeated bone fractures, dorsal kyphoscoliosis, bone fragilityand severe stature weight growthdelay. The Brain MRI revealed pituitary hypoplasia, with a fortuitous discovery of a parietal plane meningioma. The association of osteogenesis imperfecta and meningioma, as well as osteogenesis imperfecta and pituitary hypoplasia, have rarely been reported in the literature however, no accessible case of the association of the three entities has been described before within the limits of our research.The objective of our work is to demonstrate a possible pathophysiological link between these three entities.

Last modified: 2024-05-20 17:32:45