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ANTIOXIDANT ACTIVITY TEST OF SUNGKAI LEAF (Peronema canescens Jack) ETHANOL EXTRACT, N-HEXANE AND ETHYL ACETATE FRACTION

Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.9, No. 5)

Publication Date:

Authors : ; ; ; ;

Page : 126-134

Keywords : Sungkai leaves; Peronema canescens Jack; DPPH method; 2; 2-diphenyl-1-pikhrylhydrazil;

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Abstract

Research on antioxidant activity test of ethanol extract, n-hexane fraction and ethyl acetate of Sungkai leaves (Peronema canescens Jack) has been carried out. Sungkai plant is a traditional medicinal plant that is widely used for traditional medicine. Sungkai leaf secondary metabolites (Peronema canescens Jack) contain alkaloids, flavonoids, saponins, phenols, terpenoids. Sungkai leaves (Peronema canescens Jack) were extracted using maceration method with 70% ethanol solvent and fractionated using n-hexane and ethyl acetate solvents. Testing the antioxidant activity using the DPPH method (2,2-diphenyl-1-pikhrylhydrazil) obtained IC50 (Inhibition Concentration) of ethanol extract, ethyl acetate and n-hexane fractions, respectively 5.6356 µg/mL, 46.4707 µg/mL, and 153.7020 µg/mL.

Last modified: 2024-06-05 02:19:18