Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen

Three types of formulations (stable suspensions) based on collagen, chitosan, limonene and an imidazole derivative were studied through in vitro tests, from the point of view of antimicrobial activity. The results obtained on 4 standardized microorganisms, namely Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus aureus MRSA, Candida albicans, demonstrated that most of the obtained bioproducts have a local effect (inhibition diameters below 15 mm are obtained) and moderate effect (inhibition diameters located under 20 mm), except bioproducts containing collagen, chitosan, limonene and an imidazole derivative (antibiotic reagent) in mass ratio Col:Chit:Lim:CT=1:1:1:0.1, Col:Chit:Lim:CT=1:1:0:0.1 which exhibit a significant antimicrobial effect on Staphylococcus aureus and Staphylococcus aureus MRSA. These two formulations also exhibit significant antimicrobial effects for Candida albicans, for which the average inhibition diameters obtained are greater than 34 mm.