New Theory on THE Capillary Physiology Based on 40-years Research Experience |Biomedgrid

Professor Starling proposed his hypothesis on the capillary interstitial fluid transfer in 1886 [1] and later in 1896 [2] in which fluid filtration is attributed to the hydrostatic pressure and absorption to the oncotic pressure of plasma proteins. It became a law after 1948 as based on a study in which there was an experimental error based on a misconception [3] that elevating arterial and venous pressures elevate the capillary pressure, which is true for venous pressure but not true for arterial pressure as based on the common observation that a rise in venous pressure causes oedema but hypertension never does. Substantial evidence currently exists to demonstrate how the capillary works in providing fluid with oxygen and nutrients to the interstitial fluid (ISF) space as well as remove the waste products at rest and exercise when the demand for oxygen is greater. It has been proven beyond any doubt that Starling's law is in fact wrong on both of its forces and there are 21 reasons to affirm that [4]. There is new substantial evidence in both physics and physiology to prove Starling's law is wrong and the correct replacement is the hydrodynamic of the G tube [5,6] (Figure 1). I have achieved 13 new scientific discoveries in physics, physiology, and medicine, [7], that precisely prove the correctness of this new theory on capillary physiology. The received knowledge and understating of capillary physiology are reported in this article [8]. Here I summarize the new evidence based on my 40-years of research work and reports.