Collagen-Fibroin-Hydroxyapatite Scaffolds for Bone Tissue Engineering

Bone regeneration is a serious problem nowadays because of the increased number of people suffering from infections, arthritis and bond loss. The aim of the present work was to develop and characterize collagen – fibroin - hydroxyapatite matrices for hard tissue regeneration. In our study we wish to develop biomaterials which mimic bone composition and prevent allergic or toxic effects. The composites matrices obtained by freeze drying were characterized by FT-IR analysis, water uptake capacity and optic microscopy. The results obtained from analyses confirmed that collagen – fibroin - hydroxyapatite matrices exhibit proper characteristics for bone mineralization.