Vitamin D Deficiency is Associated with Hypocalcemia in Preterm Infants
Journal: Molecular and Cellular Biomedical Sciences (Vol.8, No. 2)Publication Date: 2024-07-01
Authors : Nabiel Nabiel; Hari Wahyu Nugroho; Annang Giri Moelyo;
Page : 90-5
Keywords : Vitamin D; hypocalcemia; preterm neonates;
Abstract
Background: Vitamin D deficiency results in various problems, like rickets, osteomalacia, heart problems, cancer, diabetes, and autoimmune diseases. Hypocalcemia is a common disorder among preterm infants, indicating vitamin D deficiency. This study was conducted to analyze the association of vitamin D deficiency with hypocalcemia in preterm infants. Materials and methods: A cross-sectional study was performed in preterm infants born in our hospital from December 2022 to May 2023. Venous blood was collected within the first 24 hours to assess vitamin D and calcium levels. Chi-square test and logistic regression analysis were used to assess the association of gestational age, sex, birth weight, and vitamin D with the incidence of hypocalcemia. The significance was determined with p<0.05. Results: There were 40 preterm newborns, comprising 37.5% moderately preterm, 20% very preterm, and 42.5% extremely preterm. Most subjects were female (52.5%). Low birth weight, very low birth weight, and extremely low birth weight occurred in 55%, 27.5%, and 17.5%, respectively. Vitamin D insufficiency and deficiency were observed in 20% and 80% subjects, respectively. Most subjects had hypocalcemia (62.5%). Chi-square test obtained a significant association of vitamin D deficiency with hypocalcemia (p=0.029). Conclusion: Vitamin D deficiency is significantly associated with the incidence of hypocalcemia in preterm infants.
Other Latest Articles
- Correlation between Yokohama Cytological Coding and Radiological Findings and Their Diagnostic Accuracies against Histopathology: A Retrospective Study of Palpable Breast Lesions
- Development of a Rapid and Cost-Effective Method for Estimating Plant Glucose Levels with a Glucometer
- Operations Management in Farmer Producer Organizations: A Case Study of Bagma Agri-Producer Company Ltd., Tripura
- The Prospect of Probiotics to Treat Metabolic Syndrome
- Evasion of the Immune System by Glioblastoma Multiforme: An Obstacle to Achieving Effective Therapies
Last modified: 2024-07-09 12:50:32