COMPARATIVE DIAGNOSTIC VALUE OF NEUTROPHIL-TO-LYMPHOCYTE AND PLATELET-TO-LYMPHOCYTE RATIOS FOR ACUTE APPENDICITIS

Acute appendicitis is nearly an everyday occurrence in the emergency department and consists of 10% of patients presenting to emergency service with abdominal pain. When it comes to the diagnosis of acute abdomen, appendicitis is one of the most common cause13. Early Diagnosing of appendicitis with clinical examination is Sometimes not easy and challenging14. Neutrophil-to-lymphocyte ratio (NLR) which is easily calculated from complete blood count is a simple marker of subclinical inflammation. It is also observed that Changes in the neutrophil-to-lymphocyte ratio (NLR) can be an early sign of bacterial and viral infections.Platelets are cells that help in modulating various inflammatory conditions therefore, changes in PLR may be a useful indicator of acute infection, including Acute Appendicitis.Aim is To compare Diagnostic utility of neutrophil to lymphocyte ratio vs platelet to lymphocyte ratio for diagnosis of acute appendicitis.objectives of the study as follows To calculate neutrophil to lymphocyte ratio To calculate platelet to lymphocyte ratio To compare Diagnostic utility of neutrophil to lymphocyte ratio vs platelet to lymphocyte ratio in diagnosing acute appendicitis. Our study has revealed that the Neutrophil-Lymphocyte Ratio (NLR) is significantly elevated in cases of acute appendicitis compared to the Platelet-Lymphocyte Ratio (PLR). While clinical diagnosis remains the gold standard for diagnosing acute appendicitis, NLR can also be a valuable investigative tool in the future. In our study, both NLR and PLR were elevated in response to acute appendicitis, but NLR showed a statistically significant increase. We also observed that NLR values were two to three times higher in cases of perforated or gangrenous appendicitis. Therefore, NLR is not only useful for diagnosing acute appendicitis but also for predicting complicated cases.