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Development and Characterization of Herbal Gel for Atopic Eczema

Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.7, No. 4)

Publication Date:

Authors : ; ; ; ; ;

Page : 60-64

Keywords : ;

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Abstract

Eczema manifests through itching, thickening of the skin (lichenification), scaling, swelling (oedema), and redness (erythema).. Current operation strategies include corticosteroids, which are limited due to side goods. multitudinous herbal remedies are used traditionally but unfortunately have not been validated in controlled clinical trials. Three popular traditional treatments of eczema include Indian pennywort, Walnut and Turmeric. In this study three topical phrasings (micro emulsion, gel and ointment) were prepared from extracts of Indian pennywort, Walnut and Turmeric. These phrasings were covered for stability for a period of three months. Controlled clinical trials were conducted on 360 eczema cases. Clinical parameters observed were degree of erythema, oedema, scaling, itching and lichenification. goods of each expression on these clinical parameters were compared with placebo phrasings. Micro emulsion phrasings in all cases proved to be more effective in reducing semi quantitative scores of erythema and oedema. Itching was relieved more by gel expression. The ointment showed farther effectiveness towards scaling and lichenification. Comparison of the goods of placebo and the specific phrasings was performed by chisquare statistics and set up to be largely significant. In summary it's concluded that all the phrasings could be used as promising source for treatment of eczema.

Last modified: 2024-07-21 20:48:24