Down’s Syndrome, An Emerging Threat

Background Down Syndrome has been one of the emerging threats in current society with high prevalence rate of around 3000 5000 annual birth. This requires a screening and analysis of the aetiologies and other pathophysiological factors leading to the increase in current scenario. Objective To find out the root cause of Down Syndrome To ruled out the exact cause how oxidative stress impact in Down syndrome To ruled out the exact cause how delayed pregnancy or advanced age of pregnancy impact in Down Syndrome Materials and Methods This research has been based on the approach of mixed research methodology following interpretivism and positivism research philosophy where set of different families have been selected to isolate the changes evident within them for the pathogenesis of Down syndrome Results It has been found that the evidence of trisomy is the evident feature and not the actual cause where generation of oxidative stress among the families as well as multi factorial pathways regulate the pathophysiology Conclusion Hence, considering the basic family pathology and maintaining appropriate psychophysiological correlation among the family society could reduce the increasing threat in generation of Down Syndrome among foetus. Dr. Sinchan Das | Samik Banerjee | Priyankesh Mishra "Down's Syndrome, An Emerging Threat" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-3 , June 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64793.pdf Paper Url: https://www.ijtsrd.com/medicine/pathology/64793/down's-syndrome-an-emerging-threat/dr-sinchan-das