Pan-Cancer Analysis of UBX Domain-Containing Protein 4 (UBXN4) in Human Cancers |Biomedgrid

Background: UBX domain-containing protein 4 (UBXN4) was discovered for the first time because its UBX domain can interact with p97/VCP to participate in endoplasmic reticulum-associated protein degradation (ERAD). Although there are many reports that the UBX domain-containing protein family is involved in the occurrence and development of tumors, a pan-cancer analysis of UBXN4 is not yet available. Material and Methods: We first explored the potential carcinogenic effects of UBXN4 in 33 tumors based on the datasets of TCGA (The Cancer Genome Atlas) and GEO (Gene Expression Omnibus).