Analysis of Determinants of Smoking Behavior in Vocational High Schools of Karimun District

—Introduction: Smoking behavior is a risk factor for non-communicable diseases, the number of male smokers in Indonesia is the highest in the world (third largest) after India and China. Based on GATS 2021, 34.5% of adults (70.2 million), 65.5% of men and 3.3% of women and the increasing prevalence of smoking among children aged 10-18 years from 7.2% in 2013 to 9.1% in 2018. Objective: to determine the determinants related to smoking behavior in Karimun Regency Vocational Schools. Research method: Descriptive quantitative research with a cross-sectional design (cross sectional with a sample of (356) students. Primary data source (questionnaire). Independent variables in this study include gender and smoking behavior. Data analysis includes univariate and bivariate using chi square and multivariate using multiple logistic regression. Results: univariate results, most of the 62.9% (224) respondents were non-smokers. Bivariate results relationship with smoking behavior is the gender variable, namely p = 0.000 OR = 10.387 (CI 95%). Conclusion: The variable that has the most influence on smoking behavior in Karimun Regency Vocational Schools is the gender variable to promote the movement for healthy living without smoking as early as possible in school-aged children and provide smoking cessation clinic services.