Repeated UVB Radiations Induced Thyroid Alteration and Oxidative Stress in Male Swiss Albino Mice |Biomedgrid

Due to the ozone layer depletion an increased global warming observed, which allows UVB radiation to penetrate the atmosphere and have deadly effects on people. It is thought that UVB short- and long-term radiation are exposed to daily has biological effects on organisms and humans. Concerning effect of radiations, we examine the automatic mechanism by which a specific amount of radiation induces oxidative stress and hyperthyroidism. For these examinations 12 adult male albino mice were divided into two groups: control group, UVB exposed group (2hrs/day). Mice were radiated daily for 15 consecutive days. Specimens of the thyroid gland were processed for hormonal, biochemical, histological and immunofluorescence examinations. A morphometric study and statistical analysis of the findings were performed for different groups. Compared to the control group, the specimens of the UVB exposed mice showed alteration in mean height of the thyroid follicular epithelial cells and caspase-3 expression.