Histopathological Spectrum of Lesions of Gall Bladder

Background: Gall bladder diseases exhibit a wide spectrum ranging from non-neoplastic diseases to the neoplastic. Cholecystectomy is a commonly performed abdominal surgery. Clinical diagnosis of gall bladder lesion is done based on history, physical examination and radiological findings. However, histopathological study is the gold standard method. Material and Methods: This was an observational study conducted in the Department of Pathology. Total number of specimens included was 204, maximum being cholecystectomy specimens. After proper gross examination with routine tissue processing; detailed microscopic examination was done. Results: Age of the patients ranged from 2-95 year with a mean age of 48.04 year. There was a female preponderance. Non- neoplastic lesions were more common than neoplastic. Chronic cholecystitis with cholelithiasis was the most common histopathological diagnosis. Conclusion: Histopathological examination of the gall bladder many times reveals an unusual diagnosis which may be missed radiologically and clinically thereby proving it to be the gold standard method.