Investigation of the effectiveness of various treatment methods in goats with cutaneous papillomatosis

Objective. This study investigated the recovery effects of levamisole, Tarantula cubensis extract, and levamisole + T. cubensis extract combination on goats with cutaneous papillomatosis. Materials and methods. Forty hair goats between 2 and 4 years of age in the lactation period, which were clinically diagnosed as having papillomatosis, were included in the study, and they were divided into four groups randomly, each having ten goats. No application was performed on goats in the control group. Levamisole (5 mg/kg, intramuscularly), T. cubensis extract (4 ml, subcutaneously), and both levamisole (5 mg/kg, intramuscularly) and T. cubensis extract (4 mL, subcutaneously) were administered to the goats in the levamisole group, T. cubensis extract group, and combined group, respectively, two times at weekly intervals. All animals in the groups were monitored at 15-day intervals for three months. Results. While no recovery was observed in the control group, regression was observed in only one animal's papilloma (10%). The recovery and regression rates were 40% and 40% in the levamisole group, 30% and 40% in the T. cubensis extract group, and 60% and 30% in the combined group, respectively. Conclusions. All three treatments applied in goats for treating cutaneous papillomatosis were found to be effective in different degrees. When compared between treatment groups, levamisole+T. cubensis extract combination was found to be a more effective treatment.