The effect of phenyl vinyl sulfone on Gastrothylax crumenifer in vitro

Gastrothylax crumenifer a trematode parasite of rumen in cattle causes massive damages to the host. A cystein proteases inhibitor, Phenyl vinyl sufone (PVS) which has antihelminthic and antiprotozoal effect causes lesions, structural disruption leading to gradual loss in viability, mortality and even death on prolong exposé of the chemicals to the parasites. Microscopic studies also depict the architectural and tegumental alterations on successive higher doses. Thus PVS appears to have significant roles in the protection of assets as animals.