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Peculiarities and prognostic significance of epithelial-mesenchymal transition in secondary edematous breast cancers

Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.54, No. 54)

Publication Date:

Authors : ;

Page : 396-406

Keywords : secondary edematous breast cancer epithelial-mesenchymal transition (EMT) E-cadherin immunohistochemistry N-cadherin vimentin cytokeratin 18 prognostic markers;

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Abstract

Background. Secondary edematous breast cancers (SEBC) do not possess distinct morphological or molecular characteristics, yet they are marked by more aggressive biological behavior compared to non-edematous forms. The issue of identifying morphological and molecular-biological criteria for SEBC that determine the clinical behavior of tumors remains unresolved. Purpose – was to investigate the peculiarities and prognostic significance of epithelialmesenchymal transition in SEBC.

Last modified: 2025-08-22 19:26:08