Non-Gaussian Noise Accelerates State Transitions in Bistable Biochemical Networks: A Stochastic Simulation Study
Journal: International Journal of Progressive Sciences and Technologies (IJPSAT) (Vol.52, No. 1)Publication Date: 2025-07-27
Authors : Elena Zancanaro; Margherita Bonan; Lin Wei;
Page : 461-470
Keywords : Non-Gaussian noise; bistable systems; stochastic switching; systems biology;
Abstract
This work investigates how non-Gaussian noise (e.g., Lévy fluctuations) drives state transitions in bistable biochemical networks. Using stochastic simulations (Gillespie algorithm), we show that heavy-tailed noise enhances transition rates between stable states compared to Gaussian noise. Our analysis reveals a statistical coupling between noise properties and network dynamics, offering new insights into controlling cellular decision-making processes.
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