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Non-Gaussian Noise Accelerates State Transitions in Bistable Biochemical Networks: A Stochastic Simulation Study

Journal: International Journal of Progressive Sciences and Technologies (IJPSAT) (Vol.52, No. 1)

Publication Date:

Authors : ; ; ;

Page : 461-470

Keywords : Non-Gaussian noise; bistable systems; stochastic switching; systems biology;

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Abstract

This work investigates how non-Gaussian noise (e.g., Lévy fluctuations) drives state transitions in bistable biochemical networks. Using stochastic simulations (Gillespie algorithm), we show that heavy-tailed noise enhances transition rates between stable states compared to Gaussian noise. Our analysis reveals a statistical coupling between noise properties and network dynamics, offering new insights into controlling cellular decision-making processes.

Last modified: 2025-08-24 21:30:11