Integrating Ayurveda and Modern Perspectives to Diabetic Peripheral Neuropathy and its Management A Review Article

Background Madhumeha, a subtype of Prameha, is extensively described in Ayurvedic texts and is considered equivalent to Diabetes Mellitus. One of its most debilitating complications is Diabetic Peripheral Neuropathy DPN , a chronic microvascular disorder leading to sensory, motor, and autonomic dysfunction. Although classical Ayurvedic texts do not directly describe DPN, scattered references to Upadrava Vyadhis ~complications of Prameha mirror neuropathic symptoms such as burning sensations, numbness, tingling, muscle wasting and weakness. Objective This article critically reviews Ayurvedic concepts of Madhumeha in relation to DPN and thoroughly evaluates Ayurvedic management strategies in the light of contemporary biomedical evidence. Methods Primary Ayurvedic classics alongside contemporary biomedical literature on DPN pathophysiology and its management were analysed through authentic Ayurveda and modern text as well as internet sources. Electronic databases PubMed, Scopus, AYUSH Research Portal were searched for clinical studies on Ayurvedic interventions for diabetic neuropathy, including randomized controlled trials RCTs and systematic reviews. Results Ayurvedic descriptions of Avaranajanya obstruction of Vata by Kapha Pitta and Dhatukshayaja ~tissue depletion Madhumeha provide a coherent pathophysiological model for DPN, correlating with obstruction to nerve conduction and degenerative myelin sheath damage. Panchakarma, Rasayana herbs Ashwagandha, Bala, Atibala, Guduchi , and parasurgical interventions Jalaukavacharana were found to alleviate neuropathic pain, improve nerve conduction velocity and enhance quality of life in diabetic patients. Conclusion Ayurveda provides both preventive and therapeutic models for DPN as an Upadrava of Madhumeha. An integrative approach combining Nidana Parivarjana, Panchakarma, Rasayana formulations and Jalaukavacharana has promising potential in management of DPN. However, robust multi centric RCTs are essential to validate efficacy and integrate these approaches into diabetes patients globally. Priti Engineer | Tukaram Sambhaji Dudhamal "Integrating Ayurveda and Modern Perspectives to Diabetic Peripheral Neuropathy and its Management: A Review Article" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-9 | Issue-5 , October 2025, URL: https://www.ijtsrd.com/papers/ijtsrd98703.pdf Paper URL: https://www.ijtsrd.com/medicine/ayurvedic/98703/integrating-ayurveda-and-modern-perspectives-to-diabetic-peripheral-neuropathy-and-its-management-a-review-article/priti-engineer