A Pilot Study Of Microsporidiosis And CD4 T-Cells In North- Central Nigeria

Abstract Two species of Microsporidia were identified Enterocytozoon bieneusi and Encephalitozoon cuniculi among the non-HIV and immunocompromised individuals at the Jos Plateau and Benue State Nigeria. In Jos 500 species were subjected to laboratory test and the infection rate of microsporidium species were 10.5 for gastroenteritis with 350 celll 1515.0 were HIV individuals with 200 cell l and 1919.0 AIDS patients had low CD4 counts 100 cell l. The severity of the illness was seen to have impact on the CD4 counts of the individuals in Makurdi where in both sexes 53.5 students had 100 cells l CD4 counts with corresponding fall in 365.7 Civil servants of 100 cells l cells count. Housewives were 448.8 with 50 cells l and others undefined occupational status 111.5 had CD4 counts 90 cell l. Microsporidiosis is now known to cause a serious threat in HIVAIDS patients in Nigeria with less pathogenesis among non-HIV individuals hence P1.96 critical region we accept that there was a significant difference in the distribution of Microsporidiosis among sexes in Makurdi with the x20.597.8 at 5 level of significance indicating a significant difference in sex related prevalence at the Jos Plateau. However there was high level of social behavior observed at Makurdi with a general low CD4 counts 50 cell l-100 cell l.