ASSAY METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF SOLIFENACIN SUCCINATE IN TABLETS BY UV SPECTROPHOTOMETRY

He main objective this article is to develop a simple and cheap UV spectrophotometric method for the quan titative estimation of Solifenacin succinate in tablets and validate as per ICH guidelines. The optimized method uses a solvent 0.1 N HCl for the estimation of assay of Solifenacin succinate in tablets at a detection wavelength of 210 nm. System, intraday and inter day precision are exemplified by relative standard deviation of 1.069, 0.58 and 0.77% respectively. The developed method exhibited linearity in the range of 5 - 15μg/ml. Percentage Mean recovery was found to be in the range of 98 ‐ 102, during accura cy studies. Accordingly, it is concluded that a simple and a cheap UV spectrophotometric method was developed and validated for the quantitative estimation of Solifenacin succinate in tablets as per ICH guidelines and hence it can be used for the routine a nalysis in various pharmaceutical industries. Keywords: UV, Solifenacin succinate, 0.1N HCl, method development, validation .