Ethanolic Extract of Marsdenia condurango Ameliorates Benzo[a]pyrene-induced Lung Cancer of Rats -Condurango Ameliorates BaP-induced Lung Cancer in Rats-
Journal: Journal of Pharmacopuncture (Vol.18, No. 2)Publication Date: 2015-06-30
Authors : Sourav Sikdar; Avinaba Mukherjee; Anisur Rahman Khuda-Bukhsh;
Page : 86-87
Keywords : apoptosis; caspase-3; complementary and alternative medicine (CAM); Condurango; lung cancer; reactive oxygen species (ROS);
Abstract
The original article Ethanolic Extract of Marsdenia condurango Ameliorates Benzo[a]pyrene-induced Lung Cancer of Rats (J Pharmacopuncture 2014;17(2):7-17, DOI: http://dx.doi.org/10.3831/KPI.2014.17.011) by Sourav Sikdar, Avinaba Mukherjee, and, Anisur Rahman Khuda-Bukhsh, was published with an incorrect method in abstract due to a production error. The correct method in abstract are reported below. Methods: After one month of scheduled BaP feeding (50 mg/kg body-weight), lung cancer developed after four months. BaP-intoxicated rats were then treated with Condurango (0.06 mL) twice daily starting at the end of the four months for an additional one, two and three months, respectively. Effects of Condurango were evaluated by analyzing lung histology, reactive oxygen species (ROS) and antioxidant biomarkers, DNA-fragmentation, RT-PCR (Reverese Transcriptase- Polymerase Chain Reaction), ELISA (Enzyme linked immunosorbent assay) and western blot of several apoptotic signalling markers and comparing the results against those obtained for controls. We apologize to the authors and readers.
Other Latest Articles
- Single-dose Toxicity of Water-soluble Ginseng Pharmacopuncture Injected Intramuscularly in Rats
- Single-dose Toxicity of ShinYangHur Herbal Acupuncture
- Toxicity of Single-dose Intramuscular Injection of Samjeong Pharmacopuncture in Sprague-Dawley Rats
- A Pilot Study on Single-dose Toxicity Testing of Hominis placenta Pharmacopuncture in Sprague-Dawley Rats
- Single-dose Intravenous Toxicology Testing of Daebohwalryeok Pharmacopuncture in Sprague-Dawley Rats
Last modified: 2015-07-15 10:45:38