CONTENT OF THE METABOLITE OF NITROGEN OXIDE (NO) IN BLOOD OF PATIENTS WITH THE SURGICAL INFECTION
Journal: International bilingual medical journal "MEDICUS" (Vol.1, No. 2)Publication Date: 2015-03-15
Authors : Akkaliev M.N.;
Page : 77-79
Keywords : surgical infection; endothelial dysfunction; L-arginine; urolithiasis; BPH; nitrogen oxide; endothelium-dependent vasodilation.;
Abstract
Diagnosis of endothelial dysfunction is one of the important tasks on which formation the treatment scheme directly depends. In recent years, the main attention is paid to predictive judgment of laboratory and tool markers in this con-text. The theoretical data and results of scientific researches testify that endothelial dysfunction is the main reason of development of multiple organ dysfunction and lethal outcomes by the development of syndrome of system inflamma-tory reaction. Patients with the surgical pathology of urinary system have the authentically proved increase of the content of metabolites of NO in blood that is followed by decrease in an endothelium-dependent vasodilation. This factor testifies to dysfunction of vessels endothelium. After surgery treatment, the further short-term growth of the con-tent of metabolites of NO in blood is observed and at the same time, there is an oppression of vasodilating function of endothelium.
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