Minimal Change Disease

Minimal change disease or nephrosis lipoid On light microscopy, of changes devoid. 80% of nephrotics, it does comprise Boys below 16 years pay the price. Idiopathic it is, cause unknown Possible mechanisms immune have been shown. In the net of protein loss, albumin is caught Label of selective proteinuria, it has got. No change grossly it does produce Shape and size, increase nor reduce. Changes in glomeruli and tubules are slight Noted this is on microscopy light. On EM, fl at, foot processes of podocytes seen Labeled as the foot process disease it has been. Immunofl uorescence ? absent deposits does claim Hence, “nil deposit disease” is also its name.