Toxic Compounds Analysis by High Performance Liquid Chromatography
Journal: International Journal of Clinical Pharmacology & Toxicology (IJCPT) (Vol.03, No. 03)Publication Date: 2014-10-15
Authors : Hideharu Shintani;
Page : 01-02
Keywords : Toxic Compounds; High Performance Liquid Chromatography;
Abstract
MDA can be produced from the gamma-ray sterilized thermosetting polyurethane (PU) and was found about 0.6 ppm for gammaray, 0.3 ppm for moist heat and 0.10 ppm for EOG, respectively [1]. This amount is from average three specimens. The virtual safe dose (VSD) was mathematically calculated by the one-hit model. Based on the VSD of 10-6 risk, estimation of the increased cancer risk from the highest MDA level of 0.6 ppm indicated a 1x10-7 increase for 50 kg patient exposed to dialysis three times per week for 70 years.
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