Role of LDH (Lactate dehydrogenase) in preeclampsia ? eclampsia as a prognostic marker: An observational study

Serum LDH is abnormal in a host of disorders, therefore the total serum LDH is highly sensitive but nonspecific test. In preeclampsia also LDH may be elevated and can indicate the prognosis for both mother and fetus. The present study was intended to assess the prognostic significance of the value of serum LDH as a marker of preeclampsia ? eclampsia and its severity. Higher serum LDH levels were associated with increased incidence of maternal complications like abruption placenta, renal failure HELLP syndrome, cerebrovascular accidents etc. in the present study. There was an increase in maternal morbidity with increasing serum LDH levels. To conclude high serum LDH levels have significant association with severity of disease and maternal and fetal outcomes in patients of preeclampsia and eclampsia and can be considered as a supportive prognostic tool from early third trimester.