SYNTHESIS AND BIOLOGICAL EVALUATION 1, 5- BENZOTHIAZEPINES AS POTENTIAL ANTI INFLAMMATORY AND ANTICONVULSANT ACTIVITY
Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.2, No. 9)Publication Date: 2015-09-12
Authors : Venkata Rao Vutla; Ramarao Nadendla; K. N. Rajani Kanth;
Page : 1314-1322
Keywords : 2; 4-Difluoroacetophenone; 1; 5-Dihydrobenzothiazepine; 2-Aminothiophenol; Piperidine;
Abstract
1,5-Dihydrobenzothiazepines Are Synthesized . The Compounds Have Been Screened Foranti Inflammatory And Anticonvulsant Activity. 1, 5-Dihydrobenzothiazepines Are Prepared By The Reaction Of 1,3-Diarylprop-2-Enones With O-Aminothiophenol. All The Products Were Tested For Purity By TLC And Characterized By Elemental Analysis ,IR, 1H-NMR, 13C-NMR And Mass Spectral Studies. Keywords: 2,4-Difluoroacetophenone, 1,5-Dihydrobenzothiazepine, 2-Aminothiophenol, Piperidine
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