NEW SPECTROPHOTOMETRIC METHODS FOR THE QUANTITATIVE ESTIMATION OF AZTREONAMIN FORMULATIONS

Three new spectrophotometric methods were proposed for the Quantative Estimation of Aztreonam. Method A(Tpooo) and Method B(ARS) are based on the fornation of ion association complex with the drug solution and in Method C (PNA Method) diazotization fallowed by coupling with drug in alkaline medium. Linearity ranges and RSD will be 10-70ppm and 0.23 for Method A and 40-120 ppm and 1.044 for Method B and 200-100ppm and 0.28 respectively. All these method are Accurate, precise and very effective even at low concentrations and used for the quantitive estimation of Aztreonam in commercial formulations.