SYNTHESIS AND CHARACTERIZATION OF VARIOUS 3-[3,5-BIS (TRIFLUOROMETHYL)PHENYL]-5-(SUBSTITUTED PHENYL)-1,2-ISOXAZOLE

N-[2-chloro-4-(trifluoromethyl)phenyl]-2-oxo-4-(substitutedphenyl)-6-(propan-2-yl)-1,2,3,4- tetrahydropyrimidine-5-carboxamide (4a-o) are synthesized. The synthesis of (4a-o) was achieved by acid catalysed cyclocondensation of N-[2-chloro-4-(trifluoromethyl)phenyl]-4-methyl-3- oxopentanamide, urea and Benzaldehydes. The products were characterized by FT-IR, mass spectra, 1H NMR and elemental analyses. The newly synthesized compounds were subjected to various biological activities viz., antimicrobial.