GREEN CHEMISTRY APPROACH TO NOVEL CHALCONES AND THEIR ANTIOXIDANT PROPERTIES

A series of some novel 2’Hydroxy Chalcone using inert Silica Gel (Mesh 230-400)by Microwave irradiation is reported. These newly synthesized compounds were screened for their antioxidant potential using DPPH screening method. The promising feature of this reaction is solvent free synthesis and excellent yield with high purity of compounds synthesized/targeted. All the synthesized compounds were confirmed by IR, 1HNMR and MS data. Synthesized compounds exhibited potent antioxidant activity, which is close to/ comparative to standard flavonoid quercetin.