ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF LEPISANTHES TETRAPHYLLA (SAPINDACEAE)

Lepisanthes tetraphylla (Sapindaceae) traditionally used for the treatment of Elephantiasis, skin disease, fever and claimed for its anti-convulscent property. The present study was aimed to evaluate the preliminary phytochemical analysis and anti-convulscent activity by MES (Maximal electroshock induced convulsion) and PTZ (Pentalinetetrazole induced convulsion) method. The result showed highly significant activity similar to the standard drug Phenytoin. Thus the study proof scientifically the folklore claim and traditional uses of the plant Lepisanthes tetraphylla.