PREPARATION AND STANDARDIZATION OF NISHALOUHAM VATI- A RANDOMLY PRESCRIBED CLASSICAL YOGA

Background: Nishalouham vati is an effective ayurvedic classical formulation frequently prescribed for mainly jaundice, anaemia, and diabetes. Aim: In the present study, Nishalouham vati was formulated in laboratory by the formula given in an official ayurvedic treatise Bhaisajyaratnavali written by Acharya Govinda Das and the prepared vati or pill is subjected to standardize. Materials and Method: Formulation was prepared by maintaining the aseptic conditions. Following the testing protocol of ASU drugs, (Ayurveda, Siddha and Unani) various testing parameters including organoleptic and physicochemical tests for vati like: friability, disintegration, dissolution, TLC, HPTLC etc. had been performed to fix the quality standards of the drug. Among the critical analytical study atomic absorption spectroscopy (AAS) was attempted over the sample for the detection of the limit of arsenic, lead etc. heavy metals in the sample. Microbial assay was also performed. Result: This study results a set of standard data, essential for its standardization. The values obtained after physicochemical study showed that these values were all within the limit. Conclusion: The data maybe further helpful to develop a standard operating procedure and a quality standard limit for this specific formulation. Keywords: Nishalouhamvati, Preparation, HPTLC, AAS, Microbial assay.