THE INFLUENCE OF CHRONIC FETAL NEUROINFECTIONS, IMMUNOLOGICAL STATUS, IGG IGE ISOTYPES ANTISUBSTANCES TO MYELIN BASIC PROTEIN ON PATHOLOGIC BEHAVIOR AND COURSE OF INFANTILE CEREBRAL PARALYSIS

The pattern of many demyelinating nervous disorders is often connected with various viruses. This is proved by anti-genic determinants for viruses of measles, rubella, herpetic fever and others connected with myelin basic protein (MBP). The study results conducted in our clinic proved virus infection at perinatal period can lead to the start of autoimmune processes leading to MBP responsiveness at infantile cerebral paralysis. At unfavourable course of in-fantile cerebral paralysis with resistance to medicamental treatment and rehabilitation children had the increased level of lgG and IgЕ, MBP antisubstances. Thus, virus infection leads to MBP responsiveness and non-efficiency of infantile cerebral paralysis treatment. Therefore, it is necessary to control pathological immunological and immune processes influencing the further prognosis of infantile cerebral paralysis.