Formulation, optimization and invitro evaluation of nebivolol buccal tablets
Journal: International journal of Pharmaceuticals and Health care research (Vol.01, No. 3)Publication Date: 2013-09-14
Authors : Mounica T Sudhakar babu A M S Venkateswararao P Prathap;
Page : 121-126
Keywords : Nebivolol; buccal tablets; Carbopol; Sodium alginate; Sodium carboxy methyl cellulose.;
- Formulation, optimization and invitro evaluation of nebivolol buccal tablets
- FORMULATION AND INVITRO EVALUATION OF BUCCAL DRUG DELIVERY SYSTEM OF VENLAFAXINE HYDROCHLORIC ACID TABLETS
- FORMULATION DEVELOPMENT AND EVALUATION OF BUCCAL TABLETS OF PANTOPRAZOLE
- FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF KETOROLAC TROMETHAMINE
- FORMULATION AND INVITRO EVALUATION OF SOLID DISPERSION TABLETS OF SILYMARIN
Abstract
In this study Nebivolol buccal tablets were prepared and optimized the release of Nebivolol by using Carbopol, Sodium alginate and Sodium carboxy methyl cellulose as polymers. The tablets prepared by direct compression technique and evaluated by physical parameters and invitro dissolution parameters. A total nine formulations were prepared with varying polymer concentrations. All tablets were acceptable with strength was observed in tablets formulated with Carbopol, sodium alginate and Sodium carboxy methyl cellulose. Formulation F9 showed maximum release 99% in 8 hrs. FT-IR studies showed no evidence of interaction between drug and polymers.
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Last modified: 2013-08-14 13:47:54